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AI重塑千亿级产业逻辑 钱塘如何抢占“AI+医药”新赛道?_我的网站

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A |     近日,总部位于钱塘区杭州医药港的杭州德睿智药科技有限公司(以下简称“德睿智药”)宣布完成5200万美元B轮融资。这家成立仅5年的企业,凭借自主研发的“AI制药引擎”,已将核心管线GLP-1RA小分子口服新药MDR-001推进至Ⅲ期临床试验,用实打实的研发效率刷新了业界对新药研发“双十定律”(指新药研发平均需要10年时间和10亿美元投入)的认知。

B | 在钱塘,德睿智药的突破并非孤例。

C |     

    
    

Staff members secure aircraft at Hangzhou Xiaoshan International Airport to prepare for Typhoon Dolphin on August 9, 2026. Photo: VCG
    Staff members secure aircraft at Hangzhou Xiaoshan International Airport to prepare for Typhoon Dolphin on August 9, 2026. Photo: VCG
Typhoon Dolphin made landfall in Taizhou, East China's Zhejiang Province, on Sunday afternoon, bringing strong winds up to 42 meters per second and heavy torrential rain to the coastal regions amid a red alert - the highest level in the country's typhoon warning system - issued for it earlier that day. 
Authorities in East China's Fujian have relocated nearly 100,000 residents, while coastal provinces are suspending railway services and canceled flights, making an all-out effort to mitigate possible risks.
The NMC maintained orange rainstorm and blue severe convective weather alerts at 6 am on Sunday, forecasting exceptionally heavy rainfall of 250 to 440 millimeters in some areas along the eastern coast of Zhejiang, with heavy to torrential rains expected across Jiangsu, Zhejiang, Shanghai, and Anhui between Sunday morning and Monday morning, China Central Television (CCTV) reported. 
In response to the typhoon, China's meteorological authority on Sunday upgraded its emergency response for severe meteorological disasters from Level III to Level II.
Fujian raised the emergency response level for typhoon prevention to Level II at 9 am on Sunday.
As Typhoon Dolphin gathers strength and approaches the coastal areas, Fujian's flood control authority, as of 6 pm on Saturday, deployed a total of 17,800 officials to and relocated 98,900 people from high-risk areas, Xinhua News Agency reported on Saturday.
Fujian has suspended all 115 marine engineering projects and moved 290 construction vessels to safe waters, while 55 passenger ferry routes in affected waters have been halted, chinanews.com reported. 
Meanwhile, railway services in the affected regions including Fujian, Zhejiang, Shanghai have also been suspended from Sunday to Monday, according to chinanews.com.
Fujian authorities have urged stronger safety measures for returning vessels, offshore platforms and coastal and island tourism, as well as reinforcement of aquaculture facilities. They also called for timely evacuations from flood- and landslide-prone areas to guard against secondary disasters from the typhoon and heavy rain, chinanews.com reported. 
In Zhejiang, Wenzhou city has closed all 85 A-level national tourist attractions, turned away more than 7,400 visitors and evacuated over 1,600, with the relocation effort ongoing, according to CCTV. Next, Wenzhou will next implement a "five suspensions" policy, halting outdoor group activities, classes, work, business operations and transportation.
All fishing vessels at Shitang Fishing Port in Wenling, Zhejiang, have returned to port, with all personnel evacuated ashore and maritime rescue teams on standby. Authorities urged vessels to stay off the sea during the typhoon. 
In Shanghai, Pudong and Hongqiao airports operated at reduced capacity on Sunday, with nearly 60 percent of flights canceled. A total of 1,384 flights are scheduled to be canceled including 871 at Pudong and 513 at Hongqiao. Passengers are advised to check with their airlines for the latest updates and adjust travel plans accordingly, according to CCTV.
According to Hu Xiao, meteorological analyst at the NMC, the typhoon has several notable features, including its strong intensity and expansive circulation. The typhoon also has several unusual features. Forming unusually far east, near 180°E, it has traveled more than 7,200 kilometers, making its potential landfall in China a rare event and possibly the easternmost such landfall since 1951. Its 12-day lifespan is also well above the typical seven-to-10-day average, CCTV reported. 
According to Ma Jun, director of the Institute of Public and Environmental Affairs, Typhoon Dolphin traveled a long distance and remained at typhoon or severe typhoon strength of its lifespan so far. Despite passing through some areas that were unfavorable to its development, its powerful inner core remained intact, while its extensive cloud system continued to absorb moisture and energy, fueling the potential for torrential rainfall.
The typhoon has remained at sea for more than 260 hours and experienced a rare "three rises and three falls" in intensity. Its unusually long lifespan has allowed it to absorb more moisture and energy, while repeated intensity fluctuations have complicated forecasts of its future track and intensity of wind and rainfall, according to CCTV. 
After landfall, Typhoon Dolphin may move slowly, prolonging heavy rainfall and raising the risk of extreme precipitation and related disasters. Its track later in the week remains uncertain as it could interact with the southwest monsoon and cold air from the northwest, potentially broadening and intensifying its impacts, Ma told the Global Times on Sunday.

。一场由人工智能引领的生物医药“链式反应”正在这片产业热土上加速发生——从靶点发现到分子设计,从临床试验到智慧诊疗,AI技术正以前所未有的深度和广度,重构这个千亿级产业的底层逻辑。AI破局“双十定律” 从“大海捞针”到“按图索骥”“新药研发,如同探索一片广阔而未知的宇宙。”德睿智药创始人牛张明如此形容。长期以来,全球制药行业深陷“双十定律”困局,临床成功率不足10%,传统“试错式”研发模式已触及效率天花板。德睿智药的破局之道,在于将药物研发从不可控的“经验探索”转变为由数据驱动、可计算、可迭代的“标准化工程创造”。其自主研发的一站式AI药物研发平台MAP(Molecule Arts Platform),整合了靶点发现、分子设计、多目标优化、蛋白质动态模拟等前沿技术模块,如同打造了一个虚拟实验室,帮助研究人员在近乎无穷的选择中建立优先级,并在设计早期的同时考虑活性、选择性、药代动力学、安全性和可合成性,系统性减少无效试错。

D | 成果令人瞩目:MDR-001项目仅用8个月就完成了从启动到临床前候选化合物(PCC)的研发过程,实际合成约80个小分子,并在19个月内获得IND(新药临床试验申请)批准。牛张明表示:“AI的价值不仅在于提升研发效率,更在于不断拓展人类探索生命科学的边界,让更多疾病有药可医,让更多患者从创新中获益。”德睿智药的跨越式发展,折射出钱塘“AI+医药”赛道的蓬勃活力。在浙江大学智能创新药物研究院,AI辅助药物筛选已成为新药研发的“标配”。该研究院构建了自主可控的原创靶点发现与验证技术体系,在钱塘与17家企业共建联合研发中心,累计攻克企业技术难题200余项,布局1类创新药研发项目19项,累计获得1类新药临床试验批件8项,其中两个品种已进入Ⅰ/Ⅱ期临床试验阶段。现有临床研究结果显示,相关品种较全球同类产品展现出显著的潜在竞争优势。从靶点发现到分子设计,从成药性预测到临床前评价,AI技术正在渗透新药研发全链条。恩和生物、伽奈维、新视焰等一批高成长型AI医药企业快速成长,一个覆盖“AI靶点发现—自动化实验—数字临床”的产业闭环雏形在钱塘已然显现。钱塘因何而“能” 三招解码医药产业高地为何钱塘能在“AI+医药”这一前沿赛道上实现跨越式发展?解码其发展路径,三大支撑缺一不可。

E | 首先,深厚的产业“家底”构筑最佳试验场。作为浙江省生物医药与医疗器械产业集群核心区、杭州市生物医药“一核四园多点”唯一核心区,钱塘已集聚生物医药企业1800余家,占全省四分之一、全市近半,产业规模达500亿元。默沙东、强生等6家全球十强药企在此落户,34家准独角兽企业奔腾其间,上下游链条完整、协同紧密的成熟生态,为AI技术的落地应用提供了丰富的场景和海量的数据“养料”。其次,高能级平台以校地企协同创新打通成果转化堵点。

F | 早在2020年,钱塘便与浙江大学共建省级新型研发机构——浙江大学智能创新药物研究院,一头连接基础研究,一头对接医药产业。研究院将原创靶点发现、AI分子设计等关键技术深度嵌入企业研发全过程,提供概念验证、非临床评价等全链条服务,加快实验室成果向产业化迈进的步伐。

G | 校地企深度融合形成的协同创新网络,正不断将科研优势转化为产业优势,为区域生物医药产业高质量发展持续注入动能。最后,前瞻布局与制度创新抢占新赛道。早在赛道升温之前,钱塘便抢先布局“AI+生物医药”,深化创新链、产业链、人才链、政策链、金融链、服务链“六链融合”模式,同时组建“AI智药”创新联合体,设立产业基金,出台专项政策,从药物研发、临床研究到审批上市全方位赋能。

H | 钱塘明确将“AI+医药”作为杭州建设人工智能创新发展第一城的标志性成果来打造,在全区已布局20个AI模型及智能体,建成20余个省级以上AI科研平台,集聚人工智能企业150余家。从“制造重镇”到“智造高地”,钱塘以深厚的制造业根基,引发了人工智能的“链式反应”。如今,这一“链式反应”正从智能制造向生物医药领域拓展,在钱塘江畔迸发出前所未有的创新能量。

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Published on:10:23:44